Researchers at the University of Colorado Boulder have made a significant breakthrough by creating living optical materials using engineered microbes. The project, in collaboration with the University of Rochester, focuses on tiny bioglass lenses that form on the surface of these specially designed microbes. Inspired by nature’s design principles observed in sea sponges that grow glass-like silica shells, the team engineered microbes to display similar enzymes, resulting in the formation of glass on the cell surface, effectively turning them into living microlenses.
The study, recently published in Proceedings of the National Academy of Sciences, showcases the potential for revolutionary imaging technologies in various fields, including medicine and commercial applications. By analyzing the silica, or bioglass, surrounding different bacterial strains, CU Boulder researchers demonstrated that bioengineered bacteria could produce bioglass microlenses with exceptional light-focusing properties. These microlenses, only a few micrometers in size, hold promise for high-resolution image sensors, particularly in biomedical imaging, enabling sharper visualization of subcellular features and detailed imaging of nanoscale materials.
Traditionally, creating microlenses of this caliber has been a complex and costly process, requiring advanced machinery and extreme conditions. However, the living microlenses developed through this research offer a more accessible and efficient alternative. Their small size and superior light-focusing capabilities make them ideal for various applications, from materials science to diagnostics.
With the ability to capture detailed images of microscopic pathogens like viruses and bacteria, these living optical materials could significantly enhance identification and analysis techniques. Additionally, in the field of materials science, the microlenses hold promise for capturing intricate structures at the nanoscale, offering new possibilities for research and development.
Professor Wil Srubar, a coauthor of the paper and an expert in Civil, Environmental, and Architectural Engineering at CU Boulder, emphasized the importance of leveraging nature’s design principles to create advanced materials. This approach not only showcases the ingenuity of nature but also highlights the potential for bioengineering to drive innovation in materials science and optical technologies.
The successful creation of living microlenses opens up avenues for further exploration and application in diverse industries. As technology continues to evolve, harnessing natural processes to develop cutting-edge materials could revolutionize fields such as imaging, diagnostics, and beyond. The intersection of biology and engineering exemplified in this research paves the way for future advancements in optical materials and bioengineering.
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